通過比較研究不同新冠疫苗接種之后的免疫反應(yīng)發(fā)現(xiàn),Moderna Inc.公司的新冠疫苗產(chǎn)生的抗體是輝瑞公司(Pfizer Inc.)和德國的BioNTech SE公司生產(chǎn)的新冠疫苗中的兩倍多。
比利時(shí)的一項(xiàng)針對2500名在醫(yī)院務(wù)工的員工的研究發(fā)現(xiàn):接種兩劑Moderna疫苗在未感染新冠肺炎的個(gè)體中,抗體水平平均為2881單位/毫升,相比之下,接種兩劑輝瑞疫苗在同等人群的抗體水平為1108單位/毫升。
研究結(jié)果發(fā)表在8月31日發(fā)給《美國醫(yī)學(xué)協(xié)會(huì)雜志》(Journal of the American Medical Association)的一封信中,表明這種差異可以用以下兩點(diǎn)來解釋:
· Moderna疫苗的活性成分含量更高,為100微克,而輝瑞和BioNTech的疫苗為30微克
·接種Moderna疫苗的間隔時(shí)間更長——4周,而接種輝瑞和BioNTech疫苗的間隔時(shí)間為3周
在一項(xiàng)對美國妙佑醫(yī)療國際健康系統(tǒng)(Mayo Clinic Health System)工作人員的評估中,與輝瑞的疫苗相比,Moderna疫苗能夠?qū)⒏腥拘鹿诜窝椎娘L(fēng)險(xiǎn)降低兩倍。這些研究成果早在另一項(xiàng)研究報(bào)告以及8月9日的同行評審中公布出來了。(財(cái)富中文網(wǎng))
編譯:於欣
通過比較研究不同新冠疫苗接種之后的免疫反應(yīng)發(fā)現(xiàn),Moderna Inc.公司的新冠疫苗產(chǎn)生的抗體是輝瑞公司(Pfizer Inc.)和德國的BioNTech SE公司生產(chǎn)的新冠疫苗中的兩倍多。
比利時(shí)的一項(xiàng)針對2500名在醫(yī)院務(wù)工的員工的研究發(fā)現(xiàn):接種兩劑Moderna疫苗在未感染新冠肺炎的個(gè)體中,抗體水平平均為2881單位/毫升,相比之下,接種兩劑輝瑞疫苗在同等人群的抗體水平為1108單位/毫升。
研究結(jié)果發(fā)表在8月31日發(fā)給《美國醫(yī)學(xué)協(xié)會(huì)雜志》(Journal of the American Medical Association)的一封信中,表明這種差異可以用以下兩點(diǎn)來解釋:
· Moderna疫苗的活性成分含量更高,為100微克,而輝瑞和BioNTech的疫苗為30微克
·接種Moderna疫苗的間隔時(shí)間更長——4周,而接種輝瑞和BioNTech疫苗的間隔時(shí)間為3周
在一項(xiàng)對美國妙佑醫(yī)療國際健康系統(tǒng)(Mayo Clinic Health System)工作人員的評估中,與輝瑞的疫苗相比,Moderna疫苗能夠?qū)⒏腥拘鹿诜窝椎娘L(fēng)險(xiǎn)降低兩倍。這些研究成果早在另一項(xiàng)研究報(bào)告以及8月9日的同行評審中公布出來了。(財(cái)富中文網(wǎng))
編譯:於欣
Moderna Inc.’s COVID vaccine generated more than double the antibodies of a similar shot made by Pfizer Inc. and BioNTech SE in research directly comparing immune responses to the inoculations.
A study of almost 2,500 workers at a major Belgium hospital system found antibody levels among individuals who hadn’t been infected with the coronavirus before getting two doses of the Moderna vaccine averaged 2,881 units per milliliter, compared with 1,108 units/mL in an equivalent group who got two jabs of the Pfizer shot.
The results, published on August 31 in a letter to the Journal of the American Medical Association, suggested the differences might be explained by the:
·higher amount of active ingredient in the Moderna vaccine—100 micrograms, versus 30 micrograms in Pfizer-BioNTech
·longer interval between doses of the Moderna vaccine—four weeks, versus three weeks for Pfizer-BioNTech
Moderna’s vaccine was associated with a two-fold risk reduction against breakthrough SARS-CoV-2 infections compared to Pfizer’s in a review of people in the Mayo Clinic Health System in the U.S. from January to July. The results were reported in a separate study released ahead of publication and peer review on Aug. 9.